Healstone has been closely monitoring the Kratom related regulations and technology for many years. We have developed novel ways to extract and optimize the mitragynine antigen (KRA-HS-003H) and we have also produced a purified antibody (KRAMAB-HS-002). The high-caliber paired Kratom antigen and antibody can have a cut off value as low as 100ng/ml (mitragynine). Our product has been used in different brands of Kratom IVD, and the quality is well-recognized.